Book an appointment
Choose a doctor
Dr Radoš Đinović
Doc. dr Radomir Aničić
Dr Dragan Antić
Dr Maja Bjelić
Dr Vesna Branković
Prim. dr sci. med. Bojan Bukva
Prof. dr Igor But
Dr Milena Cerović
Dr Živana Cvijan Stevančević
Dr Andrew Fishman
Dr Jesenka Grebenarević
Dr Tamara Ilisić
Dr Moma Jakovljević
Dr Neven Jokić
Dr Dejan Jovanović
Dr Marko Kenić
Dr Uroš Kenić
Dr Tamara Krstajić
Dr Frosina Krstanoska
Dr Zoran Krstanoski
Dr Goran Lekić
Col. Assoc. Professor MD Ph.D Nebojša Marić
Ass. dr Miljan Milanović
Ass. dr Vladimir Milivojević
Dr Predrag Mitrović
Dr Ljiljana Njagojević
Ass. dr Strahinja Odalović
Dr Sanja Panić
Dr Dušan Paripović
Mr. sci. med. dr Aleksandra Pavlović
Dr Sara Dunja Pempelfort
Dr Vladislav Pešić
Dr Dejan Pličević
Prof. dr Dragan Radovanović
Dr Mihailo Radovanović
Prof. dr Tomislav Ranđelović
Dr Nataša Ristić
Dr Nina Ristić
Dr Predrag Rodić
Dr Milan Rodić
Dr Raša Romanović
Dr Snežana Rsovac
Dr Jovan Rudić
Spec. dr med. Antonela Sabati Rajić
Dr Milan Savić
Dr Predrag Savić
Dr Milan Slavković
Dr Bogdan Spiridonescu
Prof. dr Aleksandar Sretenović
Dr Milan Stajić
Dr Saša Tomović
Doc. dr Aleksandar Vlahović
Dr Nataša Đurđević
Dr Nataša Vlahović
Ass. dr sci. med. Rastko Živić
Spec. Snežana Živković
Dr Ivanka Janković
Dr Vera Vojinović Golubović

For additional information
contact us:

* fields marked with an asterisk (*) are mandatory

For additional information
contact us:

Privacy Policy and Terms of Use

What is azoospermia?

Azoospermia is a medical condition characterized by the absence of sperm in a man’s ejaculate, which is a significant cause of male infertility. There are two main types of azoospermia: obstructive and non-obstructive. Obstructive azoospermia occurs when there is a blockage in the reproductive tract that prevents sperm from reaching the ejaculate. Non-obstructive azoospermia, on the other hand, occurs due to problems with sperm production in the testes, which can be caused by genetic factors, hormonal imbalances, or testicular damage.

Diagnosis

The diagnosis of azoospermia requires a thorough medical evaluation, which usually includes multiple consecutive semen tests to confirm azoospermia, as one test can be inadequate due to possible variations in sperm production or the presence of mucus that can block sperm. Hormone level testing, such as FSH (follicle-stimulating hormone), LH (luteinizing hormone), and testosterone, helps determine if there is a problem in hormonal regulation that could affect sperm production. Genetic testing can identify specific genetic causes of non-obstructive azoospermia, such as Klinefelter’s syndrome or mutations in the Y chromosome. Ultrasound of the testes helps identify possible structural abnormalities in the testes or the presence of varicocele. In some cases, a direct tissue sample from the testes may be needed for microscopic analysis to determine the presence of spermatogenesis within the testes.

treatment

The treatment for azoospermia depends on the cause. For obstructive azoospermia, surgical procedures to remove the blockage or bypass blocked pathways can be effective. For non-obstructive azoospermia, treatment can be more challenging. In some cases, hormonal therapy may help stimulate sperm production. If testicular biopsy shows the presence of sperm, sperm extraction techniques directly from the testes (such as TESE) can be used in conjunction with IVF procedures to achieve pregnancy.
In all cases, it is important for couples to work with a specialized reproductive health team that can provide support and counseling through the complex process of diagnosis and treatment.